Wales have made just one change for the second consecutive week after Dan Biggar was passed fit despite a shoulder problem.
It is a shoulder injury that has forced Wales' one change, as they Alex Cuthbert heads home with Josh Adams – who was dropped for Cuthbert last week – coming in.
Owen Watkin comes in on the bench, while Dillon Lewis recovers from a shoulder injury, that saw him leave the ground in a sling, to stay at tighthead prop.
Wales boss Wayne Pivac was delighted to have the opportunity to play for the series win in the final test, and that his squad had managed to stay fit through a brutal tour.
“Most people had written us off before we left Wales, and to be in this position with an opportunity to win this series is a great position for us to be in.
“However, it has been a tough training week because we have been a bit banged up, as you would expect after two very physical Test matches.
“So to have the majority of the squad that we arrived on these shores with available is a pretty good state to be in, and we are really looking forward to the weekend.
“The atmosphere on match-day has been excellent. South African fans are very loud, they support their side and they let you know what they are thinking of the occasion.”
Wales' victory last week, coming after they narrowly missed out on a result in the first test, was their first win ever in the Rainbow Nation.
Should they win again, they will be the first team to win a series in South Africa in a quarter of a century, since the British & Irish Lions' triumph in 1997.
