Harlequins will kick-off the inaugural Champions Cup at The Stoop with the reception of Castres on October 17.
With the fixtures announced for the opening two rounds of the new-look European competition, Premiership champions will travel to Racing Metro the following day while Toulon will start their quest but an historic hat-trick at home against the Scarlets.
But the clash of the round will be a remake of last year's semi-final between Saracens and Clermont with the English side hosting the French giants at Allianz Park.
Round 1
October 17
Harlequins v Castres (19:45)
October 18
Sale v Munster (13:00)
Saracens v Clermont (15:15)
Glasgow v Bath (15:15)
Racing Métro v Northampton (18:15)
Leicester v Ulster (19:45)
October 19
Ospreys v Treviso (13:00)
Toulouse v Montpellier (14:00)
Toulon v Scarlets (16:15)
Leinster Rugby v Wasps (17:15)
Round 2
October 24
Munster v Saracens (19:45)
October 25
Ulster v Toulon (13:00)
Bath v Toulouse (15:15)
Northampton v Ospreys (17:15)
Montpellier v Glasgow (18:15)
Scarlets v Leicester (19:45)
October 26
Castres v Leinster (14:00)
Clermont v Sale (16:15)
Wasps v Harlequins (17:15)
Treviso v Racing Métro (18:15)
