Mako Vunipola will start at loose-head for England in Saturday’s RBS 6 Nations match against Italy at the Stadio Olimpico.
The Saracene prop replaces Joe Marler who is with his partner ahead of the imminent birth of their first child.
As a result, London Wasp Matt Mullan comes on to the replacements’ bench.
England Head Coach Stuart Lancaster said: “It is important that Joe is with his partner at this exciting time. Family must always come first and everyone in the squad wishes them well. We have prepared for being without Joe and we have no doubt Mako will slot straight in and perform, as will Matt Mullan from the bench should he get an opportunity.”
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